The success of protein therapeutics depends on their efficacy, safety, and stability. Specifically, stability studies play a crucial role in identifying factors that lead to aggregation and degradation. Traditional methods for analyzing stability often require large sample volumes, are time-consuming, and lack reliability. In this webinar, Dikran Khachadourian will introduce Halo Labs’ innovative Aura® PTx platform, which uses advanced imaging and fluorescence microscopy to rapidly size, count, and characterize proteins and other particles in mixed samples with minimal volumes. Attendees will explore its key applications, including developability assessments and USP788 testing.

Key Learning Objectives

  • Master protein, particle, and product characterization as early as early-phase development using only 5uL of sample leveraging a modernized approach of membrane microscopy.
  • Explore how Fluorescence Membrane Microscopy (FMM) can be used to differentiate between subpopulations of particulates, such as protein aggregates, polysorbate degradants, and extrinsic contaminants.
  • Learn why Backgrounded Membrane Imaging (BMI) has become an emerging technique for lot release testing and generating USP 788-compliant data.

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