The Aura™ system takes the guesswork out of your particle analysis so you’ll know exactly how to get to your best formulation. Fluorescence Membrane Microscopy (FMM) technology tells you which particles are protein aggregate and which are extrinsic non-particle protein while an optional second fluorescence channel enables custom fluorescence assays that can identify other molecules specific to your process.
Combine this with the Backgrounded Membrane Imaging (BMI) technology that powers the Horizon system for a low volume, high-throughput subvisible particle analysis system. Translation? You can now perform particle screening as early as lead optimization and pre-formulation testing to gain key drug stability insights earlier, reducing development risk and time to market. And did we mention the Aura counts and measures 100% of your sample so sample focus and flow rates won’t ever bias your data? With Aura, you’ll never need to worry about what you’re missing!
Definitively determine if your particles are protein or not in your stability analysis and contaminant detection by using Thioflavin T, a fluorescent dye that specifically binds to protein aggregates.
Fluorescence Labeling of Your Choice
Get the flexibility needed to identify other particles in your formulation. Choose between channels for TMA, Bodipy, DiI, to identify hydrophobic entities or other molecules specific to your process. Don’t see the channel you want? Select your own custom excitation and emission!
Only the Aura system measures 100% of your sample and keeps all of the particles in the same plane of focus. Get accurate counts right away, without having to optimize the frame rate and flow rate.
Looking for ways to increase your efficiency? Not only is the 96-well membrane plate compatible with liquid handlers, but the Aura system is fully robotic-compatible as well.
The ring light works as a status bar, keeping you posted on your experiment’s progress, even across the room.
Large Size Range
1 µm – 5 mm. See the smallest subvisible to the largest visible particles, all in one tool.